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camizestrant — SERENA-4

AstraZeneca · $AZN
Standard Review Phase 3
Catalyst Date
September 1, 2026
Time Remaining
154 days
Review Type
Standard (10 mo)

Live Company Data NYQ

Updated 4m ago · Data: FMP
Current Price
$193.88 +31.37%
+$46.30 today
Day: $192.61 – $194.64
Market Cap
N/A
52-Week Range
$122.48
$212.71
Current price is at 79% of 52-week range
⚠️ Financial data is for informational purposes only. Not investment advice. Prices may be delayed.

Indication

HR+/HER2- advanced breast cancer — first-line (frontline, traditional design)

Key Notes

SERENA-4 Phase 3 readout expected H2 2026 (Fierce Pharma). Traditional first-line design: camizestrant + Pfizer Ibrance (palbociclib) vs standard endocrine therapy + CDK4/6i in frontline HR+/HER2- advanced breast cancer. Distinct from SERENA-6 (the emergent ESR1 mutation "switch" design that supports the NDA under ODAC review April 30). If both SERENA-6 and SERENA-4 succeed, camizestrant could displace aromatase inhibitors as the dominant endocrine backbone for HR+ breast cancer.
⚠️ Not Investment Advice: This information is provided for educational purposes only. PDUFA dates are FDA target action dates, not guaranteed approval dates. The FDA may extend the review period, issue Complete Response Letters, or take unexpected actions. Probability of approval scores are based on historical base rates and do not account for drug-specific factors. Always consult a financial advisor before making investment decisions.

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